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产品详情
操作说明
注意事项
Product Information
|
Description |
FOXO3A rabbit polyclonal antibody |
|
Protein full name |
Forkhead box protein O3 |
|
Synonyms |
FOXO3, AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A, forkhead box O3 |
|
Immunogen |
Recombinant protein corresponding to Mouse FOXO3A |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
71 kDa |
|
Observed MW. |
97 kDa |
|
Uniprot ID |
Q9WVH4, O43524 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
liver cancer, glioma, lung, brain |
Background
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Images
|
|
Western blot analysis of FOXO3A (GB11092-1) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室