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Anti -FEN1 Rabbit pAb

价格: 在线咨询
货号:
KT012121
产品规格:
100ul
Applications:
WB
Species:
H/M
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

FEN1 rabbit polyclonal antibody

Protein full name

Flap endonuclease 1

Synonyms

FEN-1, Flap structure-specific endonuclease 1, Fen1, Fen-1, DNase IV, flap structure endonuclease 1, hFEN 1, Maturation factor 1, MF1, RAD2

Immunogen

Recombinant protein corresponding to Mouse FEN1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

42 kDa

Observed MW.

45 kDa

Uniprot ID

P39748, P39749




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse

1: 500-1: 1000

lung, testis, small intestine




Background


FEN1(Flap endonuclease-1) is the prototypical member of the 5’-nuclease superfamily, whose activities span a range of cellular pathways involved in DNA replication and genome maintenance . FEN1 is a structure-selective metallonuclease essential for Okazaki fragment maturation through efficient removal of 5’ flaps resulting from strand displacement during lagging-strand synthesis. FEN1 is overexpressed in multiple cancer types, and has been suggested both as a biomarker relating to prognosis and disease progression and as a potential therapeutic target.




Images

Picture 1.png

Western blot analysis of FEN1 (GB111455) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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