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产品详情
操作说明
注意事项
Product Information
|
Description |
FEN1 rabbit polyclonal antibody |
|
Protein full name |
Flap endonuclease 1 |
|
Synonyms |
FEN-1, Flap structure-specific endonuclease 1, Fen1, Fen-1, DNase IV, flap structure endonuclease 1, hFEN 1, Maturation factor 1, MF1, RAD2 |
|
Immunogen |
Recombinant protein corresponding to Mouse FEN1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
42 kDa |
|
Observed MW. |
45 kDa |
|
Uniprot ID |
P39748, P39749 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse |
1: 500-1: 1000 |
lung, testis, small intestine |
Background
FEN1(Flap endonuclease-1) is the prototypical member of the 5’-nuclease superfamily, whose activities span a range of cellular pathways involved in DNA replication and genome maintenance . FEN1 is a structure-selective metallonuclease essential for Okazaki fragment maturation through efficient removal of 5’ flaps resulting from strand displacement during lagging-strand synthesis. FEN1 is overexpressed in multiple cancer types, and has been suggested both as a biomarker relating to prognosis and disease progression and as a potential therapeutic target.
Images
|
|
Western blot analysis of FEN1 (GB111455) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室