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Anti -MRPL12 Rabbit pAb
价格：
在线咨询
货号：
KT012098
产品规格：
100 μL
Applications：
WB | IHC
Species：
M,R/H
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
MRPL12 rabbit polyclonal |
|
Protein full name |
39S ribosomal protein L12, mitochondrial |
|
Synonyms |
L12mt, MRP-L12, 5c5-2, Mitochondrial large ribosomal subunitprotein bL12m, MRPL12, MRPL7, RPML12 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human MRPL12 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Mitochondrion |
|
Predicted MW. |
21 kDa |
|
Observed MW. |
21 kDa |
|
Uniprot ID |
Q9DB15 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
stomach, colon, breast |
|
IHC |
Human |
1: 500-1: 1000 |
stomach cancer |
Background
MRPL12 is a component of the 39S subunit of mammalian mitochondrial ribosomes, and is encoded by a nuclear gene. The protein forms a homodimer, localizes predominantly to mitochondria and binds to the large mitochondrial ribosomal subunit. It is required for CycD/Cdk4- induced cell growth. In addition, forming a ribosomal stalk with MRPL7, MRPL12 is required for the recruitment of translation elongation factors Tu and G to the large ribosomal subunit . It also a part of a novel regulatory mechanism that coordinates mitochondrial transcription with translation and/or ribosome biogenesis during human mitochondrial gene expression.
Images
|
|
Western blot analysis of MRPL12 (GB111410) at dilution of 1: 1000 Lane 1: Mouse stomach tissue lysate Lane 2: Mouse colon tissue lysate Lane 3: Rat breast tissue lysate Lane 4: Rat stomach tissue lysate |
|
Immunohistochemistry analysis of paraffin-embedded human stomach cancer using MRPL12 (GB111410) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室