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Product Information
Description |
MRPS22 rabbit polyclonal antibody |
Protein full name |
28S ribosomal protein S22, mitochondrial |
Synonyms |
MRP-S22, S22mt, Mrps22, Rpms22, C3orf5, COXPD5, GIBT, GK002 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse MRPS22 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
41 kDa |
Observed MW. |
41 kDa |
Uniprot ID |
Q9CXW2 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Mouse, Rat |
1: 500-1: 1000 |
skeletal muscle, heart, liver, testis |
Background
MRPS22,
also named as C3orf5, RPMS22 and S22mt, is a component of the
mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA
and about 30 distinct proteins. Defects in MRPS22 are the cause of
combined oxidative phosphorylation deficiency type 5 (COXPD5). MRPS22 is
a 360-amino-acid protein that has been found in a limited number of
species, having no ortholog in fungi or prokaryotes. The exact location
of MRPS22 in the three dimensional structure of the ribosome and its
exact function are currently unknown. Recently, a MRPS22 defect was
shown to strongly hamper assembly of the small ribosomal subunit,
whereas assembly of the large subunit and part of the small subunit were
only mildly affected.
Images
|
Western blot analysis of MRPS22 (GB111366) at dilution of 1: 500 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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