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Product Information
Description |
PDXP rabbit polyclonal antibody |
Protein full name |
Pyridoxal phosphate phosphatase |
Synonyms |
PLP phosphatase, Chronophin, Pdxp, Cin, Plp, Plpp |
Immunogen |
Recombinant protein corresponding to Mouse PDXP |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
32 kDa |
Observed MW. |
32 kDa |
Uniprot ID |
P60487 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse |
1: 500-1: 1000 |
heart, brain |
Background
Protein serine phosphatase that dephosphorylates 'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho-tyrosine (By similarity). Pyridoxal phosphate (PLP) phosphatase, which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), with order of substrate preference PLP > PNP > PMP.
Images
|
Western blot analysis of Pdxp (GB111072) at dilution of 1: 500
|
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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