服务热线
400-1016-218
联系方式
- 手机：400-1016-218
- Q Q：355185756
- 邮箱：355185756@qq.com
- 地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
BIK rabbit polyclonal antibody |
|
Protein full name |
Inward rectifier potassium channel 2 |
|
Synonyms |
Inward rectifier K(+) channel Kir2.1, IRK-1, Potassium channel, inwardly rectifying subfamily J member 2, Kcnj2, Irk1 |
|
Immunogen |
Recombinant protein corresponding to Mouse BIK |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
48 kDa |
|
Observed MW. |
55 kDa |
|
Uniprot ID |
P35561, Q64273 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain |
Background
KCNJ2, also named as HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7 and SQT3, belongs to the inward rectifier-type potassium channel family. KCNJ2 probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ2 can be blocked by extracellular barium or cesium. Defects in KCNJ2 are the cause of long QT syndrome type 7 (LQT7). Defects in KCNJ2 are the cause of short QT syndrome type 3 (SQT3).
Images
|
|
Western blot analysis of KIR2.1 (GB111433) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
凡合肥万物生物科技有限公司销售的产品均有严格的质量保证。如发现产品存在包装规格疑问，请于收货之日起七日内向我公司总部或当地办事处提出，并请保证该产品，以备本公司进行核对检验。如果发现有质量问题，请于收货后一月内保留产品50%以上的量，以便本公司回收产品进行质检，确认产品质量。如逾期，则视为已经对本公司产品进行验收。 声明：如发生产品索赔事宜，本公司仅在产品价格范围内酌情赔偿，恕不接受超出产品价格范围之赔偿。客户在使用过程中有任何技术问题可以拨打技术售后服务电话我们随时给予解答。
合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室