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产品详情
操作说明
注意事项
Product Information
|
Description |
MCK10 rabbit polyclonal antibody |
|
Protein full name |
Epithelial discoidin domain-containing receptor 1 |
|
Synonyms |
Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2, CAK, EDDR1, NEP, NTRK4, PTK3A, MCK-10, CD167a, DDR1, RTK6, TRKE |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human MCK10 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cell membrane, Secreted |
|
Uniprot ID |
Q08345 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Human |
1:400-1:1000 |
colon, colon cancer, esophagus, ovarian cancer |
Background
This protein belongs to a subfamily of tyrosine kinase receptors. The Tyrosine kinase functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases.
Images
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|
Immunohistochemistry of paraffin embedded human colon using DDR1 (GB111290) at dilution of 1:450 (400x lens) |
|
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Immunohistochemistry of paraffin embedded human colon cancer using DDR1 (GB111290) at dilution of 1:450 (400x lens) |
|
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Immunofluorescence of paraffin embedded human colon cancer using DDR1 (GB111290) at dilution of 1:400 (400x lens) |
|
|
Immunofluorescence of paraffin embedded human esophagus using DDR1 (GB111290) at dilution of 1:400 (400x lens) |
|
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Immunofluorescence of paraffin embedded human ovarian cancer using DDR1 (GB111290) at dilution of 1:400 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室