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产品详情
操作说明
注意事项
Product Information
|
Description |
Skp1 rabbit polyclonal antibody |
|
Protein full name |
S-phase kinase-associated protein 1 |
|
Synonyms |
Cyclin-A/CDK2-associated protein p19, S-phase kinase-associated protein 1A, p19A, p19skp1, Skp1, Skp1a |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Skp1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Nucleus, cytoplasm |
|
Uniprot ID |
Q6PEC4 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Human, Rat |
1: 1500-1: 3000 |
colon, heart, liver, lung |
Background
SKP1A is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. SKP1A also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor.
Images
|
|
Immunohistochemistry of paraffin embedded rat heart using SKP1 (GB111230) at dilution of 1:1600 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded rat lung using SKP1 (GB111230) at dilution of 1:1600 (400x lens) |
|
|
Immunofluorescence of paraffin embedded human colon using SKP1 (GB111230) at dilution of 1:1600 (400x lens) |
|
|
Immunofluorescence of paraffin embedded human liver using SKP1 (GB111230) at dilution of 1:1600 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室