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产品详情
操作说明
注意事项
Product Information
|
Description |
UBE2E3 rabbit polyclonal antibody |
|
Protein full name |
Ubiquitin-conjugating enzyme E2 E3 |
|
Synonyms |
E2 ubiquitin-conjugating enzyme E3, UbcM2, Ubiquitin carrier protein E3, Ubce4, Ubiquitin-conjugating enzyme E2-23 kDa, Ubiquitin-protein ligase E3, Ube2e3, UBCH9 |
|
Immunogen |
Recombinant protein corresponding to Mouse UBE2E3 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
23 kDa |
|
Observed MW. |
23 kDa |
|
Uniprot ID |
Q969T4, P52483 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 1000-1: 1500 |
testis, brain, kidney |
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases or E3s. UBE2E3 is a member of the E2 ubiquitin-conjugating enzyme family. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48', as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.
Images
|
|
Western blot analysis of Ube2e3 (GB111203) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室