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Anti -Asialoglycoprotein Receptor 1/HL-1 Rabbit pAb
价格：
在线咨询
货号：
KT011927
产品规格：
100 μL
Applications：
WB
Species：
MR
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
ASGR1 rabbit polyclonal antibody |
|
Protein full name |
Asialoglycoprotein receptor 1 |
|
Synonyms |
ASGP-R 1, Hepatic lectin 1, HL-1, mHL-1, Asgr1, Asgr |
|
Immunogen |
Recombinant protein corresponding to Mouse ASGR1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
33 kDa |
|
Observed MW. |
42 kDa |
|
Uniprot ID |
P34927, P02706 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
liver |
Background
Asialoglycoprotein receptor (ASGPR), also known as the hepatic galactose/N-acetylglucosamine (GlcNAc) receptor or Ashwell receptor, is a C-type lectin expressed exclusively in hepatic parenchymal cells. ASGPR consists of two subunits, a major subunit (ASGR1, HL-1) and a minor subunit (ASGR2, HL-2), and specifically recognizes terminal β-linked galactose or GlcNAc on circulating glycoproteins or cells. This receptor plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins that contain terminal galactose or GlcNAc residues. ASGPR may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery.
Images
|
|
Western blot analysis of ASGR1 (GB111336) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室