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产品详情
操作说明
注意事项
Product Information
|
Description |
GRP94 rabbit polyclonal antibody |
|
Protein full name |
Endoplasmin |
|
Synonyms |
94 kDa glucose-regulated protein, GRP-94, ERp99, Heat shock protein 90 kDa beta member 1, Polymorphic tumor rejection antigen 1, Tumor rejection antigen gp96, Hsp90b1, GRP94, Tra-1, Tra1 |
|
Immunogen |
Recombinant protein corresponding to Mouse GRP94 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
92 kDa |
|
Observed MW. |
100 kDa |
|
Uniprot ID |
P14625, P08113, Q66HD0 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
lung, brain |
Background
GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells.
Images
|
|
Western blot analysis of GRP94 (GB111280) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室