服务热线
400-1016-218
全国统一服务热线
400-1016-218
科研好帮手 专业生产商
本公司产品仅供科研使用
Product Information
Description |
JAM-A rabbit polyclonal antibody |
Protein full name |
Junctional adhesion molecule A |
Synonyms |
JAM-A, Junctional adhesion molecule 1, JAM-1, CD321, F11r, Jam1, Jcam, Jcam1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse JAM-A |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
33 kDa |
Observed MW. |
35 kDa |
Uniprot ID |
Q9Y624, O88792, Q9JHY1 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
liver, colon, small intestine |
Background
Seems to play a role in epithelial tight junction formation. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin super family gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as a receptor for reovirus, a ligand for the integrin LFA1, involved in leukocyte transmigration, and a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Images
|
Western blot analysis of Junctional adhesion molecule A (GB111062) at dilution of 1: 500 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
合肥万物生物科技有限公司
客服热线:400-1016-218
QQ:355185756
地址:安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室