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Anti -PGP9.5 Mouse mAb

价格: 在线咨询
货号:
KT011741
产品规格:
100 μL
Applications:
WB/IHC/IF
Species:
HMR/HMR
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

PGP9.5 mouse monoclonal antibody

Protein full name

Ubiquitin carboxyl-terminal hydrolase isozyme L1

Synonyms

UCH-L1, Neuron cytoplasmic protein 9.5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, Uchl1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse PGP9.5

Isotype

IgG1

Purity

Affinity purification

Subcellular location

Cytoplasm, Endoplasmic reticulum, Membrane

Predicted MW.

27 kDa

Observed MW.

27 kDa

Uniprot ID

P09936, Q9R0P9, Q00981




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 1000-1: 2000

cerebral cortex, hippocampus, brain

IHC/IF

Human, Mouse, Rat

1: 1000-1: 2000

brain, colon, esophagus cancer, stomach




Background


UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons. This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm . And UCHL1 is a Parkinson's disease susceptibility gene.




Images


Picture 1.png

Western blot analysis of PGP9.5 (GB12159) at dilution of 1: 1000

Picture 2.png Immunohistochemistry of paraffin embedded human esophagus cancer using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens)

Picture 3.png

Immunohistochemistry of paraffin embedded human stomach using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens)

Picture 4.png

Immunohistochemistry of paraffin embedded mouse brain using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens)

Picture 5.png

Immunohistochemistry of paraffin embedded mouse colon using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens)

Picture 6.png

Immunohistochemistry of paraffin embedded rat brain using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens)

Picture 7.png

Immunohistochemistry of paraffin embedded rat colon using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens)

Picture 8.png

Immunohistochemistry of paraffin embedded rat stomach using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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