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Anti -Nurr1 Rabbit pAb

价格: 在线咨询
货号:
KT011516
产品规格:
Applications:
WB | IHC | IF
Species:
H,M H,M H,M
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

Nurr1 rabbit polyclonal

Protein full name

Nuclear receptor subfamily 4 group A member 2

Synonyms

NUR-related factor 1, Orphan nuclear receptor NURR1, Nr4a2, Nurr1

Immunogen

Recombinant protein corresponding to Mouse Nurr1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Predicted MW.

67 kDa

Observed MW.

67 kDa

Uniprot ID

P43354, Q06219, Q07917




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 800

brain

IHC

Human, Mouse

1: 200-1: 800

kidney cancer, breast cancer, tonsil, thyroid, brain, spleen

IF

Human, Mouse

1: 200-1: 800

brain




Background


NR4A2 belongs to the orphan nuclear receptor (NR) family referred to as NR4A family, which have been implicated in cell cycle regulation, apoptosis, inflammation, metabolism and more recently in carcinogenesis . NR4A2 also has a role in the expression of several proteins that are necessary for the synthesis and regulation of dopamine (DA), such as tyrosine hidroxilase, dopamine transporter, vesicular monoamine transporter 2 and cRET [PMID:22294735]. Act as a transcriptional regulator, NR4A2 is essential for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development.




Images


Western blot analysis of Nurr1 (GB111267) at dilution of 1: 800
Lane 1: Jurkat cell lysate
Lane 2: SH-SY5Y cell lysate
Lane 3: HepG2 cell lysate
Lane 4: HT29 cell lysate
Lane 5: Mouse brain tissue lysate
Lane 6: Rat brain tissue lysate

Immunohistochemistry analysis of paraffin-embedded human kidney cancer using Nurr1 (GB111267) at dilution of 1: 800


Immunohistochemistry analysis of paraffin-embedded human breast cancer using Nurr1 (GB111267) at dilution of 1: 200

Immunohistochemistry analysis of paraffin-embedded human tonsil using
Nurr1 (GB111267) at dilution of 1: 400

Immunohistochemistry analysis of paraffin-embedded human thyroid using
Nurr1 (GB111267) at dilution of 1: 200



Immunohistochemistry analysis of paraffin-embedded mouse brain using
Nurr1 (GB111267) at dilution of 1: 800

Immunohistochemistry analysis of paraffin-embedded mouse spleen using
Nurr1 (GB111267) at dilution of 1: 200

Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using
Nurr1 (GB111267) at dilution of 1: 400




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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