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Anti -Alpha-synuclein Rabbit pAb

价格: 在线咨询
货号:
KT011698
产品规格:
100 μL
Applications:
WB/IHC/IF/ICC/IF
Species:
MR/HMR/H
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

Alpha-synuclein rabbit polyclonal antibody

Protein full name

Alpha-synuclein

Synonyms

Snca, α-synuclein, SNCA, NACP, PARK1, PARK4, PD1, synuclein alpha

Immunogen

Recombinant protein corresponding to Mouse α-synuclein

Isotype

IgG

Purity

Affinity purification

Subcellular location

CytoplasmMembraneNucleusSecreted

Predicted MW.

14 kDa

Observed MW.

19 kDa

Uniprot ID

O55042, P37377



Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 1000

cerebral cortex, brain, cerebellum, spinal cord

IHC/IF

Human, Mouse, Rat

1: 1000-1: 2000

cerebellum, brain

ICC/IF

Human

1: 500-1: 1000

SH-SY5Y



Background


Alpha-synuclein is a protein that, in humans, is encoded by the SNCA gene. It is abundant in the brain while smaller amounts are found in the heart, muscles, and other tissues. In the brain, alpha-synuclein is found mainly at the tips of nerve cells (neurons) in specialized structures called presynaptic terminals. Within these structures, alpha-synuclein interacts with phospholipids and proteins. Presynaptic terminals release chemical messengers, called neurotransmitters, from compartments known as synaptic vesicles.




Images


Western blot analysis of a-synuclein (GB11773) at dilution of 1: 500

Immunohistochemistry analysis of paraffin-embedded mouse tumor using 

snca (GB11773) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse tumor using 

snca (GB11773) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse brain using 

snca (GB11773) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using 

snca (GB11773) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded rat cerebellum using 

snca (GB11773) at dilution of 1: 1000

Immunohistochemistry analysis of 4% paraformaldehyde-fixed SH-SY5Y cells using Alpha-synuclein GB11773 at dilution of 1: 800




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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