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产品详情
操作说明
注意事项
Product Information
|
Description |
TTBK1 rabbit polyclonal antibody |
|
Protein full name |
Tau-tubulin kinase 1 |
|
Synonyms |
KIAA1855, TTBK1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse TTBK1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
142 kDa |
|
Observed MW. |
130 kDa |
|
Uniprot ID |
Q6PCN3 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse |
1: 300-1: 800 |
brain, heart, testis |
Background
TTBK1 (tau tubulin kinase 1), also known as BDTK (brain-derived tau kinase), is a 1,321 amino acid protein that contains one protein kinase domain and belongs to the serine/threonine protein kinase family. Localized to the cytoplasm and expressed at high levels in brain and at lower levels in testis and spinal cord, TTBK1 functions as a serine/threonine kinase that can phosphorylate Tau (a protein involved in tubulin polymerization) on threonine, tyrosine and serine residues. Specifically, TTBK1 uses divalent cations, such as magnesium and manganese, to catalyze the ATP-dependent transfer of a phosphate group onto Tau, creating a phosphoprotein and ADP.
Images
|
Western blot analysis of TTBK1 (GB113900) at dilution of 1: 800 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室