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Anti -Phospho-TAU (S202/T205) Rabbit pAb
价格：
在线咨询
货号：
KT011642
产品规格：
100 μL
Applications：
WB/IHC/IF
Species：
HMR/HMR
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
Phospho-TAU (S202/T205) rabbit polyclonal antibody |
|
Protein full name |
Microtubule-associated protein tau |
|
Synonyms |
Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU, P-TAU |
|
Immunogen |
KLH conjugated Synthetic phosphopeptide corresponding to Human TAU (S202/T205) |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm, Cytoskeleton, Secreted, Cell membrane, Cell projection |
|
Predicted MW. |
79 kDa |
|
Observed MW. |
50-80 kDa |
|
Uniprot ID |
P10636-8 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, hippocampus, liver, spleen |
|
IHC/IF |
Human, Mouse, Rat |
1: 600-1: 1200 |
brain |
Background
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity .The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both .Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Images
|
Western blot analysis of phospho-TAU (S202/T205) (GB113883) at dilution of 1: 1000 |
|
Western blot analysis of phospho-TAU (S202/T205) (GB113883) at dilution of 1: 1000 The figure above was treated with phospho-blocking pepide, the figure below was treated with non-phospho- blocking pepide. |
|
Immunohistochemistry of paraffin embedded mouse brain using phospho-TAU (S202/T205) at dilution of 1: 1200 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室