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Product Information
Description |
BSCL2/Seipin rabbit polyclonal |
Protein full name |
Seipin |
Synonyms |
Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog, Bscl2, Gng3lg, MNCb-2630, HMN5, MGC4694, SPG17, Spastic paraplegia 17 |
Immunogen |
Recombinant protein corresponding to Mouse BSCL2/Seipin |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
43 kDa |
Observed MW. |
46 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 300-1: 800 |
brain, kidney, testis |
Background
This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).
Images
|
Western blot analysis of BSCL2 (GB113213) at dilution of 1: 800 |
|
Western blot analysis of BSCL2 (GB113213) at dilution of 1: 800 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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