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产品详情
操作说明
注意事项
Product Information
|
Description |
MRP8 rabbit polyclonal antibody |
|
Protein full name |
Protein S100-A8 |
|
Synonyms |
S100A8, 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF, P8, S100 calcium |
|
Immunogen |
Recombinant protein corresponding to Mouse MRP8 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Secreted, Cytoskeleton, Cell membrane |
|
Uniprot ID |
P05109, P27005, P50115 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Human, Mouse, Rat |
1:500-1:3000 |
ovarian cancer, spleen, stomach |
Background
S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.
Images
|
Immunohistochemistry of paraffin embedded mouse spleen using S100A8 (GB11421) at dilution of 1:1500 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat spleen using S100A8 (GB11421) at dilution of 1:1500 (400x lens) |
|
Immunofluorescence of paraffin embedded human ovarian cancer using S100A8 (GB11421) at dilution of 1:1500 (400x lens) |
|
Immunofluorescence of paraffin embedded mouse spleen using S100A8 (GB11421) at dilution of 1:1500 (400x lens) |
|
Immunofluorescence of paraffin embedded rat stomach using S100A8 (GB11421) at dilution of 1:1500 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室