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Product Information
Description |
Iba1 rabbit polyclonal |
Protein full name |
Allograft inflammatory factor 1 |
Synonyms |
AIF-1, AIF1, G1, IBA1, IRT 1, Protein G1, Ionized calcium-binding adapter molecule 1, MRF1, Microglia response factor, BART 1, AIF1 protein |
Immunogen |
Recombinant protein corresponding to Mouse Iba1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Human, Mouse, Rat |
1: 500-1: 1000 |
oligodendroglioma, brain, cerebellum |
IF |
Human, Mouse, Rat |
1: 500-1: 1000 |
oligodendroglioma, brain, cerebellum |
Background
AIF1, also named as G1, IBA1 or daintain/AIF-1, is a 143 amino acid cytoplasmic, inflammation response scaffold protein. It is constitutively expressed in monocytes and macrophages and is known to be involved in macrophage activation. It is a marker of activated macrophage. Despite a lack of detailed knowledge on the in vivo physiological functions of AIF-1, there is growing evidence that shows its aberrant expression contributes to the pathogenesis of many autoimmune diseases, including rheumatoid arthritis. AIF1 is an actin-binding protein that enhances membrane ruffling and RAC activation. It enhances lymphocyte migration and the actin-bundling activity of LCP1.
Images
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Immunohistochemistry analysis of paraffin-embedded human oligodendroglioma using iba1 (GB113502) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using iba1 (GB113502) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using iba1 (GB113502) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat cerebellum using iba1 (GB113502) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed human oligodendroglioma using iba1 (GB113502) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using iba1 (GB113502) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat brain using iba1 (GB113502) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse cerebellum using iba1 (GB113502) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat cerebellum using iba1 (GB113502) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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