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Anti -SIRP alpha Rabbit pAb
价格：
在线咨询
货号：
KT011555
产品规格：
100 μL
Applications：
WB | IHC | IF
Species：
M,R/M,R
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
SIRP alpha rabbit polyclonal antibody |
|
Protein full name |
Tyrosine-protein phosphatase non-receptor type substrate 1 |
|
Synonyms |
Sirpa, SIRPA, BIT, CD172A, MFR, MYD-1, P84, PTPNS1, SHPS1, SIRP, SIRPα, Signal-regulatory protein alpha, Signal regulatory protein alpha |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse SIRPα |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cell membrane |
|
Predicted MW. |
56 kDa |
|
Observed MW. |
100 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain, cerebellum, cerebral cortex |
|
IHC/IF |
Mouse, Rat |
1: 500-1: 3600 |
kidney, lung, spleen |
Background
Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation.
Images
|
|
Western blot analysis of SIRPA (GB11914) at dilution of 1: 500 |
|
Immunohistochemistry of paraffin embedded mouse kidney using SIRPA (GB11914) at dilution of 1: 3600 (250x lens) |
|
Immunohistochemistry of paraffin embedded rat lung using SIRPA (GB11914) at dilution of 1: 3600 (250x lens) |
|
|
Immunofluorescence of paraffin embedded mouse lung using SIRPA (GB11914) at dilution of 1: 1000 (300x lens)
|
|
|
Immunofluorescence of paraffin embedded rat spleen using SIRPA (GB11914) at dilution of 1: 1000 (300x lens)
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室