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产品详情
操作说明
注意事项
Product Information
|
Description |
Chymase rabbit polyclonal |
|
Protein full name |
Chymase |
|
Synonyms |
Alpha-chymase, Mast cell chymase 1, Mast cell chymase 5, mMCP-5, Mast cell protease I, Cma1, Mcpt5 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Chymase |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Mouse, Rat |
1: 1000-1: 2000 |
skin, stomach, uterus |
|
IF |
Mouse, Rat |
1: 500-1: 1000 |
skin, stomach, uterus |
Background
This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse skin using Chymase (GB111085) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat skin using Chymase (GB111085) at dilution of 1: 1000 |
|
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Immunohistochemistry analysis of paraffin-embedded mouse stomach using Chymase (GB111085) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat uterus using Chymase (GB111085) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室