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Anti -Amyloid Precursor Protein Rabbit pAb
价格：
在线咨询
货号：
KT011534
产品规格：
100 μL
Applications：
WB/IHC/IF
Species：
MR/MR
购买数量：
产品详情
操作说明
注意事项
Product Information
|
Description |
Amyloid Precursor Protein rabbit polyclonal antibody |
|
Protein full name |
Amyloid-beta A4 protein |
|
Synonyms |
ABPP, APP, Alzheimer disease amyloid A4 protein homolog, Amyloid precursor protein, AG, CVAP, PN-II, Cerebral vascular amyloid peptide, Beta-amyloid precursor protein |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Amyloid Precursor Protein |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cell membrane, Nucleus, Secreted, Cytoplasm |
|
Predicted MW. |
87 kDa |
|
Observed MW. |
100 kDa |
|
Uniprot ID |
P12023, P08592 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
cerebellum, brain, hippocampus |
|
IHC/IF |
Mouse, Rat |
1: 600-1: 1200 |
cerebellum, substantia nigra |
Background
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities.
Images
|
|
Western blot analysis of APP (GB112075) at dilution of 1: 500 |
|
|
Immunofluorescence of paraffin embedded mouse cerebellum using APP (GB112075) at dilution of 1: 600 (200x lens) |
|
|
Immunofluorescence of paraffin embedded mouse substantia nigra using APP (GB112075) at dilution of 1: 600 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat cerebellum using APP (GB112075) at dilution of 1: 600 (200x lens) |
|
|
Immunofluorescence of paraffin embedded rat substantia nigra using APP (GB112075) at dilution of 1: 600 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室