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产品详情
操作说明
注意事项
Product Information
|
Description |
FCGBP rabbit polyclonal |
|
Protein full name |
IgGFc-binding protein |
|
Synonyms |
Fcgamma-binding protein antigen, FcgammaBP, FCGBP, Fc fragment of IgG binding protein |
|
Immunogen |
Recombinant protein corresponding to Human FCGBP |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Secreted |
|
Uniprot ID |
Q9Y6R7 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Human, Rat |
1: 500-1: 1500 |
colon |
Background
Fc (Ig constant fragment) receptors ensure protection of the host against foreign antigens, such as microorganisms and pathogens, by removing Ig-coated antigen complexes from circulation. Fc receptors are present on lymphoid and myeloid derivatives, where they mediate endocytosis of Ig-antigen complexes, antibody production in B cells through T cell antigen presentation, cytotoxicity and the release of cytokines and reactive oxygen species. The Fc γ-binding protein (FCGBP) interacts with the Fc portion of IgG and MUC2 to mediate the maintenance of the mucosal structure. FCGBP is a 5,405 amino acid protein that contains twelve TIL (trypsin inhibitory-like) domains and thirteen VWFD domains.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded human colon using FCGBP (GB112030) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat colon using FCGBP (GB112030) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室