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Product Information
Description |
AICDA rabbit polyclonal |
Protein full name |
Single-stranded DNA cytosine deaminase |
Synonyms |
Activation-induced cytidine deaminase, AID, Cytidine aminohydrolase, Aicda, CDA2, HIGM2, Integrated into Burkitt's lymphoma cell line Ramos |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse AICDA |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
24 kDa |
Observed MW. |
24 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse |
1: 500-1: 1000 |
lymph gland, spleen |
Background
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
Images
|
Western blot analysis of AICDA (GB112019) at dilution of 1: 1000 Lane 1: RAW264.7 cell lysate Lane 2: HL-60 cell lysate Lane 3: Mouse lymph gland tissue lysate Lane 4: Mouse spleen tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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