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产品详情
操作说明
注意事项
Product Information
|
Description |
CD73 rabbit polyclonal |
|
Protein full name |
5'-nucleotidase |
|
Synonyms |
5'-NT, CD73, Nt5e, Nt5, Nte, 5' nucleotidase precursor, E5NT, Ecto-5'-nucleotidase |
|
Immunogen |
Recombinant protein corresponding to Mouse CD73 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
64 kDa |
|
Observed MW. |
64 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
liver, kidney, retina |
Background
CD73 is a glycosyl-phosphatidylinositol (GPI)-anchored adhesion protein that catalyzes the dephosphorylation of extracellular purine and pyrimidine nucleotides to their corresponding bioactive nucleosides. CD73 is a dimer of two identical subunits that depends on GPI to link with the external face of the plasma membrane. Similar to other GPI-anchored proteins, CD73 mediates co-stimulatory signals in T cell activation. CD73 has few structural variants, yet elicits diverse biological function through differential regulation in endothelial cells (EC), subpopulations of B and T cells, germinal center follicular dendritic cells and on thymic medullary reticular fibroblasts.
Images
|
|
Western blot analysis of CD73 (GB111807)
at dilution of 1: 1000 Lane 1: Hela cell lysate Lane 2: Mouse liver tissue lysate Lane 3: Mouse kidney tissue lysate Lane 4: Rat liver tissue lysate Lane 5: Rat kidney tissue lysate Lane 6: Rat retina tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室