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产品详情
操作说明
注意事项
Product Information
|
Description |
Mannose Receptor rabbit polyclonal |
|
Protein full name |
Macrophage mannose receptor 1 |
|
Synonyms |
CD206, CLEC13D, Macrophage mannose receptor 1, Mannose receptor, mannose receptor, C type 1, MMR, MRC1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Mannose Receptor |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Mouse |
1: 400-1: 800 |
lung |
|
IF |
Mouse |
1: 400-1: 800 |
lung |
Background
CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane glycoprotein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded mouse lung with LPS treated for 24h using CD206 (GB113497) at dilution of 1: 800 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed mouse lung with LPS treated for 24h using CD206 (GB113497) at dilution of 1: 800 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室