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Product Information
Description |
CD169 rabbit polyclonal |
Protein full name |
Sialoadhesin |
Synonyms |
Sialic Acid Binding Ig Like Lectin 1, Sialoadhesin, SIGLEC-1, SN, CD1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CD169 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location |
Cell membrane,Secreted |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Human, Mouse, Rat |
1:500-1:3000 |
tonsil,lymph node |
IF |
Human, Mouse, Rat |
1:500-1:1000 |
tonsil,lymph node |
Background
Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis.
Images
Immunohistochemistry analysis of paraffin-embedded human tonsil using CD169(GB11299) at dilution of 1:500 |
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Immunohistochemistry analysis of paraffin-embedded rat lymph node using CD169(GB11299) at dilution of 1:500
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Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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