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产品详情
操作说明
注意事项
Product Information
|
Description |
CD163 rabbit polyclonal |
|
Protein full name |
Scavenger receptor cysteine-rich type 1 protein M130 |
|
Synonyms |
CD163, M130, MM130, SCARI1, CD163 molecule |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human CD163 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Q86VB7 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Human |
1: 500-1: 1000 |
liver cancer, lung, tonsil |
Background
Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded human liver cancer using CD163 (GB113152) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin-embedded human lung using CD163 (GB113152) at dilution of 1: 1000 |
|
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Immunohistochemistry analysis of paraffin-embedded human tonsil using CD163 (GB113152) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室