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产品详情
操作说明
注意事项
Product Information
| Description | CD163 rabbit polyclonal |
| Protein full name | Scavenger receptor cysteine-rich type 1 protein M130 |
|
Synonyms |
CD163, M130, MM130, SCARI1, CD163 molecule |
| Immunogen |
Recombinant protein corresponding to Mouse CD163 |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location |
Secreted,Cell membran |
| Uniprot ID |
Q2VLH6 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Mouse, Rat |
1:200-1:1000 |
spleen |
|
IF |
Mouse, Rat |
1:200-1:1000 |
spleen |
Background
Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity).
Images
|
Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD163 (GB11340-1) at dilution of 1:300
|
|
Immunohistochemistry analysis of paraffin-embedded mouse Inflammatory spleen using CD163 (GB11340-1) at dilution of 1:500
|
|
Immunohistochemistry analysis of paraffin-embedded rat Inflammatory spleen using CD163 (GB11340-1) at dilution of 1:300
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室