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Product Information
Description |
Il-10 mouse monoclonal |
Protein full name |
Interleukin-10 |
Synonyms |
IL10, CSIF, GVHDS, IL-10, IL10A, TGIF, interleukin 10, Cytokine Synthesis Inhibitory Factor, Interleukin-10 precursor |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse IL-10 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Rat |
1: 1000-1: 2000 |
lung, pneumonia |
IF |
Rat |
1: 500-1: 1000 |
lung, pneumonia |
Background
IL-10 is a cytokine with multiple, pleiotropic, effects in immunoregulation and inflammation. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway.
Images
Immunohistochemistry analysis of paraffin-embedded rat lung using IL-10 (GB12108) at dilution of 1: 2000. |
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Immunohistochemistry analysis of paraffin-embedded rat pneumonia using IL-10 (GB12108) at dilution of 1: 1000. |
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Immunofluorescence analysis of paraffin-embedded mouse Inflammatory lung using IL-10 (GB11108) at dilution of 1:300. |
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Immunofluorescence analysis of paraffin-embedded rat Inflammatory lung using IL-10 (GB11108) at dilution of 1:600. |
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Immunofluorescence analysis of paraffin-embedded rat Inflammatory spleen using IL-10 (GB11108) at dilution of 1:600. |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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