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Product Information
Description |
Il-10 rabbit polyclonal |
Protein full name |
Interleukin-10 |
Synonyms |
IL10, CSIF, GVHDS, IL-10, IL10A, TGIF, interleukin 10, Cytokine Synthesis Inhibitory Factor, Interleukin-10 precursor |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse IL-10 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
P22301, P29456 |
Applications
applications |
species |
dilution |
Positive tissue |
IHC |
Mouse, Rat |
1: 200-1: 1000 |
spleen, lung |
IF |
Mouse, Rat |
1: 200-1: 1000 |
pneumonia, splenitis, spleen, thymus |
Background
IL-10 is a cytokine with multiple, pleiotropic, effects in immunoregulation and inflammation. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway.
Images
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Immunohistochemistry analysis of paraffin-embedded rat lung IL-10 (GB11108) at dilution of 1:300 |
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Immunohistochemistry analysis of paraffin-embedded rat spleen IL-10 (GB11108) at dilution of 1:300 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat pneumonia using IL-10 (GB11108) at dilution of 1: 300
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Immunofluorescent analysis of paraformaldehyde-fixed rat spleen using IL-10 (GB11108) at dilution of 1: 300
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Immunofluorescent analysis of paraformaldehyde-fixed rat splenitis using IL-10 (GB11108) at dilution of 1: 300
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Immunofluorescent analysis of paraformaldehyde-fixed rat thymus using IL-10 (GB11108) at dilution of 1: 300 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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