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产品详情
操作说明
注意事项
Product Information
|
Description |
IL-9 rabbit polyclonal |
|
Protein full name |
Interleukin-9 |
|
Synonyms |
Il9, IL9, HP40, IL-9, P40, interleukin 9 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse IL-9 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Secreted |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Mouse, Rat |
1: 1500-1: 3000 |
splenitis, enteritis |
|
IF |
Mouse, Rat |
1: 750-1: 1500 |
splenitis, enteritis |
Background
Il-9 is a cytokine secreted by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins namely STAT1, STAT3 and STAT5 and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. Interleukin-9 has also shown to inhibit melanoma growth in mice. Additionally, it gives rise to the multiplication of hematologic neoplasias and also Hodgkin's lymphoma in humans but IL-9 also has antitumor properties in solid tumors,for example melanoma.
Images
|
Immunohistochemistry analysis of paraffin-embedded mouse splenitis using IL-9 (GB11684) at dilution of 1: 1500
|
|
Immunohistochemistry analysis of paraffin-embedded rat enteritis using IL-9 (GB11684) at dilution of 1: 1500
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室