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Product Information
Description |
M-CSF Receptor rabbit polyclonal |
Protein full name |
Macrophage colony-stimulating factor 1 receptor |
Synonyms |
CSF1R, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R, Colony stimulating factor 1 receptor, MCSF receptor, M-CSF Receptor |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse M-CSF Receptor |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cell membrane |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Mouse, Rat |
1: 500-1: 3000 |
splenitis, spleen |
IF |
Mouse, Rat |
1: 500-1: 1000 |
spleen |
Background
Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein. The encoded protein is a single pass type I membrane protein and acts as the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most of the biological effects of this cytokine. Ligand binding activates CSF1R through a process of oligomerization and trans-phosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases.
Images
Storage
Storage |
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles |
Storage Buffer |
PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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