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产品详情
操作说明
注意事项
Product Information
|
Description |
TSLP rabbit polyclonal |
|
Protein full name |
Thymic stromal lymphopoietin |
|
Synonyms |
Thymic stroma-derived lymphopoietin, Tslp, TSLP protein, thymic stromal lymphopoietin |
|
Immunogen |
Recombinantproteincorrespondingto Mouse TSLP |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Secreted |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Mouse, Rat |
1: 500-1: 1500 |
lung, brain, skin, heart |
|
IF |
Mouse, Rat |
1: 500-1: 1000 |
prostate, lung |
Background
TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c ( ) dendritic cells, naive CD4 ( ), and CD8 ( ) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation. TSLP influences the regulation of the positive selection of regulatory T cells and maintenance of peripheral CD4 ( ) T cell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse lung using TSLP(GB111664) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat lung using TSLP(GB111664) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using TSLP(GB111664) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using TSLP(GB111664) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse skin using TSLP(GB111664) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat skin using TSLP(GB111664) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat skin using TSLP(GB111664) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat heart using TSLP(GB111664) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse prostate using TSLP (GB111664) at dilution of 1: 650 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat lung using TSLP (GB111664) at dilution of 1: 650 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室