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产品详情
操作说明
注意事项
Product Information
|
Description |
LIFR rabbit polyclonal |
|
Protein full name |
Leukemia inhibitory factor receptor |
|
Synonyms |
LIF receptor, LIF-R, D-factor/LIF receptor, CD118, Lifr, SJS2, STWS, LIF-R, LIFR |
|
Immunogen |
Recombinant protein corresponding to Mouse LIFR |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
123 kDa |
|
Observed MW. |
190 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
heart, liver, kidney, placenta |
Background
LIFR, also known as CD118 is a subunit of a receptor for leukemia inhibitory factor (LIF). LIF is a pleiotropic cytokine of the interleukin-6 family which affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR is the low-affinity binding chain that, together with the high-affinity converter subunit gp130, forms a high-affinity receptor complex that mediates the action of LIF. The high-affinity complex also binds a related cytokine, oncostatin M. LIFR has also been identified as a breast cancer metastasis suppressor that functions through the HIPPO-YAP pathway.
Images
|
Western blot analysis of LIFR (GB111476) at dilution of 1: 1000 Lane 1: Mouse heart tissue lysate Lane 2: Mouse liver tissue lysate Lane 3: Mouse kidney tissue lysate Lane 4: Mouse placenta tissue lysate Lane 5: Rat liver tissue lysate Lane 6: Rat placenta tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室