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Anti -Thyroid Peroxidase/TPO Mouse mAb

价格: 在线咨询
货号:
DRF101610
产品规格:
50 μL
Applications:
Species:
购买数量:
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产品详情 操作说明 注意事项

Product Information


Gene Name TPO
Protein Name Thyroid peroxidase (TPO) (EC 1.11.1.8)
Human Gene Id 7173
Human Swiss Prot No P07202
Immunogen Synthesized peptide derived from human Thyroid Peroxidase(TPO)
Specificity This antibody detects endogenous levels of human Thyroid Peroxidase(TPO)
Source Mouse/IgG1, Kappa
Concentration 1 mg/ml
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.




Applications


Applications Species Dilution
IHC、IF Human 1:200-1:500




Background

thyroid peroxidase(TPO) Homo sapiens This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011],




Images



Immunohistochemical analysis of paraffin-embedded Follicular thyroid carcinoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval.

Immunohistochemical analysis of paraffin-embedded Follicular thyroid carcinoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval.




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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