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Product Information
Description |
CD31 mouse monoclonal |
Protein full name |
Platelet endothelial cell adhesion molecule |
Synonyms |
CD31 Antigen, EndoCAM, PECAM-1, GPIIA, PECA1, CD31 |
Immunogen |
Human recombinant CD31 protein expressed in CHO cells |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Human |
1: 300-1: 600 |
gastric cancer, liver cancer |
IF |
Human |
1: 300-1: 600 |
stomach, breast cancer, para-cancer lung, lung cancer |
Background
Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome 17. PECAM-1 plays a key role in removing aged neutrophils from the body. PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte transmigration, angiogenesis, and integrin activation.
Images
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Immunohistochemistry analysis of paraffin-embedded human gastric cancer using CD31(GB12064) at dilution of 1: 600 |
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Immunohistochemistry analysis of paraffin-embedded human liver cancer using CD31(GB12064) at dilution of 1: 600 |
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Immunofluorescent analysis of paraformaldehyde-fixed human stomach using CD31(GB12064) at dilution of 1: 600 |
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Immunofluorescent analysis of paraformaldehyde-fixed human breast cancer using CD31(GB12064) at dilution of 1: 600 |
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Immunofluorescent analysis of paraformaldehyde-fixed human para-cancer lung using COLIII(GB11629) (green) + COLI(GB11022-3) (red) + Actin(GB111364) (yellow) +CD31(GB12064) (orange) at dilution of 1: 600 |
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Immunofluorescent analysis of paraformaldehyde-fixed human lung cancer using Actin(GB111364) (green) + CD31(GB12064) (spred) + CD3(GB11014) (pink) at dilution of 1: 600 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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