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产品详情
操作说明
注意事项
Product Information
|
Gene Name |
MUC5AC MUC5 |
|
Protein Name |
Mucin-5AC (MUC-5AC) (Gastric mucin) (Lewis B blood group antigen) (LeB) (Major airway glycoprotein) (Mucin-5 subtype AC, tracheobronchial) (Tracheobronchial mucin) (TBM) (Fragments) |
|
Human Swiss Prot No |
P98088 |
|
Immunogen |
Synthesized peptide derived from human MUC5AC |
|
Specificity |
This antibody detects endogenous levels of human MUC5AC |
|
Source |
Mouse/IgG1, Kappa |
|
Concentration |
1 mg/ml |
|
Purification |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Human |
1:200-1:500 |
gastric carcinoma, colon adenocarcinoma, rectal adenocarcinoma |
Background
Mucin is a high M.W. (>1,000 kDa) glycoprotein, expressed by mucus cells of the gastric epithelium and by goblet cells of the fetal, precancerous and cancerous colon, but not by those of the normal colon. It also appears in other epithelial tissues, which are embryologically derived from the foregut (epigastric and bronchial epithelium) and in Müller ducts (mucus cells of the endocervix and urethral epithelium near the prostatic utriculus). The expression of MUC5AC has been frequently observed in gastric carcinomas and may be used as a marker of gastric differentiation.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded human gastric carcinoma using MUC5AC (GB14112) at dilution of 1: 200 |
|
|
Immunohistochemistry analysis of paraffin-embedded human colon adenocarcinoma using MUC5AC (GB14112) at dilution of 1: 200 |
|
|
Immunohistochemistry analysis of paraffin-embedded human rectal adenocarcinoma using MUC5AC (GB14112) at dilution of 1: 200 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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