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产品详情
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注意事项
Product Information
| Gene Name | CDH16 UNQ695,PRO1340 |
| Protein Name | Cadherin-16 (Kidney-specific cadherin) (Ksp-cadherin) |
| Human Gene Id | 1014 |
| Human Swiss Prot No | O75309 |
| Immunogen | Synthesized peptide derived from human KSP-Cadherin |
| Specificity | This antibody detects endogenous levels of human KSP-Cadherin |
| Source | Mouse/IgG1, Kappa |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Applications
| Applications | Species | Dilution |
|
| IHC、IF | Human | 1:200-1:500 |
|
Background
cadherin 16(CDH16) Homo sapiens This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011],
Images
|
Immunohistochemical analysis of paraffin-embedded Chromophobe cell renal carcinoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. |
|
Immunohistochemical analysis of paraffin-embedded Chromophobe cell renal carcinoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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