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Product Information
Gene Name | GCG |
Protein Name | Glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXM) (OXY); Glucagon; Glucagon-like peptide 1 (GLP-1) (Incretin hormone); Glucagon-like peptide 1(7-37) (GLP-1(7 |
Human Gene Id | 2641 |
Human Swiss Prot No | P01275 |
Immunogen | Synthesized peptide derived from human Glucagon |
Specificity | This antibody detects endogenous levels of human Glucagon |
Source | Mouse/IgG1, Kappa |
Concentration | 1 mg/ml |
Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Applications
Applications | Species | Dilution |
|
IHC、IF | Human | 1:200-1:500 |
|
Background
glucagon(GCG) Homo sapiens The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008],
Images
Immunohistochemical analysis of paraffin-embedded Pancreas. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval. |
|
Immunohistochemical analysis of paraffin-embedded Pancreas. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citric acid ,pH6.0 was used for antigen retrieval. |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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