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产品详情
操作说明
注意事项
Product Information
| Gene Name | ENG END |
| Protein Name | Endoglin (CD antigen CD105) |
| Human Gene Id | 2022 |
| Human Swiss Prot No | P17813 |
| Immunogen | Synthesized peptide derived from human CD105(Endoglin) |
| Specificity | This antibody detects endogenous levels of human CD105(Endoglin) |
| Source | Mouse/IgG1, Kappa |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Applications
| Applications | Species | Dilution |
|
| IHC、IF | Human | 1:200-1:500 |
|
Background
Endoglin encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in Endoglin cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Endoglin may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for Endoglin.
Images
|
Immunohistochemical analysis of paraffin-embedded Placenta. 1, Antibody was diluted at 1:200(4°,overnight). 2, TRIS-EDTA of pH8.0 was used for antigen retrieval. |
|
Immunohistochemical analysis of paraffin-embedded Renal clear cell carcinoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, TRIS-EDTA of pH8.0 was used for antigen retrieval. |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
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地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室