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Product Information
Description | Survivin Rabbit monoclonal |
Protein full name | Baculoviral IAP repeat-containing protein 5 |
Synonyms | API4, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, BIRC5, EPR 1, IAP4, SURVIVIN |
Immunogen |
Recombinant protein corresponding to Mouse Survivin |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Nucleus, Cytoplasm. |
Uniprot ID | Q15392,O70201,Q9JHY7 |
Applications
Applications | Species | Dilution | Positive Tissue |
IHC | Human | 1: 250 - 1: 500 | urinary bladder carcinoma, colonic adenocarcinoma, bladder carcinoma |
Background
Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules.
Images
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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