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产品详情
操作说明
注意事项
Product Information
|
Description |
S100 beta mouse monoclonal |
|
Protein full name |
Protein S100-B |
|
Synonyms |
S100B, NEF, S100, S100-B, S100beta, S100 calcium binding protein B, S100β |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse S100B |
|
Isotype |
IgG1 |
|
Purity |
Affinity purification |
|
Subcellular location |
Nucleus, Cytoplasm |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Mouse, Rat |
1: 1000-1: 2000 |
brain |
Background
S100B is glial-specific and is expressed primarily by astrocytes, but not
all astrocytes express S100B. It has been shown that S100B is only
expressed by a subtype of mature astrocytes that ensheath blood
vessels and by NG2-expressing cells.This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes,
inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing
CNS, it acts as a neurotrophic factor and neuronal survival protein.
In the adult organism. it is usually elevated due to nervous system
damage, which makes it a potential clinical marker.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded mouse brain using S100B (GB12359) at dilution of 1: 2000 |
|
|
Immunohistochemistry analysis of paraffin-embedded mouse brain using S100B (GB12359) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室