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产品详情
操作说明
注意事项
Product Information
| Description |
HSP60 mouse monoclonal |
| Protein full name |
60 kDa heat shock protein, mitochondrial |
|
Synonyms |
HSP60, HSP-60, HuCHA60, CPN60, 60 KDa Chaperonin, P60 Lymphocyte Protein, Heat Shock Protein 60 |
| Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse HSP60 |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location |
Cytoplasm |
|
Predicted MW. |
60 kDa |
|
Observed MW. |
60 kDa |
| Uniprot ID |
Applications
| Applications |
WB |
IHC |
| Species |
Human, Mouse, Rat |
Human, Mouse, Rat |
| Dilution |
1: 500-1: 1000 |
1: 1000-1: 2000 |
| Positive tissue |
Hela, HepG2, MCF7, NIH/3T3, PC12 |
colon, colon cancer, kidney |
Background
Heat shock protein 60 (HSP60) is a mitochondrial chaperonin that is typically held responsible for the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix. In addition to its role as a heat shock protein, HSP60 functions as a chaperonin to assist in folding linear amino acid chains into their respective three-dimensional structure. Through the extensive study of groEL, HSP60’s bacterial homolog, HSP60 has been deemed essential in the synthesis and transportation of essential mitochondrial proteins from the cell's cytoplasm into the mitochondrial matrix. Further studies have linked HSP60 to diabetes, stress response, cancer and certain types of immunological disorders.
Images
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Western blot analysis of HSP60 (GB12243) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded human colon using HSP60 (GB12243) at dilution of 1: 2000 |
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IImmunohistochemistry analysis of paraffin-embedded human colon cancer using HSP60 (GB12243) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse kidney using HSP60 (GB12243) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat kidney using HSP60 (GB12243) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室