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产品详情
操作说明
注意事项
Product Information
|
Description |
PGP9.5 mouse monoclonal |
|
Protein full name |
Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
|
Synonyms |
UCH-L1, Neuron cytoplasmic protein 9.5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, Uchl1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse PGP9.5 |
|
Isotype |
IgG1 |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Predicted MW. |
25 kDa |
|
Observed MW. |
25 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 1000-1: 2000 |
brain, cortex, hippocampus |
|
IHC |
Human, Mouse, Rat |
1: 1000-1: 2000 |
glioma, neuroendocrine tumor, stomach, colon, brain |
Background
UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons. This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm . And UCHL1 is a Parkinson's disease susceptibility gene.
Images
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Western blot analysis of PGP9.5 (GB12159) at dilution of 1: 2000 Lane 1: U87 cell lysate Lane 2: N2A cell lysate Lane 3: Human glioma cell lysate Lane 4: Mouse brain tissue lysate Lane 5: Mouse cortex tissue lysate Lane 6: Mouse hippocampus tissue lysate Lane 7: Rat brain tissue lysate Lane 8: Rat cortex tissue lysate Lane 9: Rat hippocampus tissue lysate |
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Immunohistochemistry analysis of paraffin-embedded human glioma using PGP9.5 (GB12159) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded human neuroendocrine tumor using PGP9.5 (GB12159) at dilution of 1: 2000 |
|
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Immunohistochemistry analysis of paraffin-embedded human stomach using PGP9.5 (GB12159) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded mouse colon using PGP9.5 (GB12159) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat colon using PGP9.5 (GB12159) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using PGP9.5 (GB12159) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室