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产品详情
操作说明
注意事项
Product Information
|
Description |
Iba1 mouse monoclonal |
|
Protein full name |
Allograft inflammatory factor 1 |
|
Synonyms |
AIF1, AIF-1, IBA, IRT-1, IRT1, allograft inflammatory factor 1 |
|
Immunogen |
Recombinant protein corresponding to Mouse Iba1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoskeleton, Plasma membrane |
|
Uniprot ID |
O70200, P55009 |
Applications
|
applications |
species |
dilution |
Positive tissue |
|
IHC |
Mouse, Rat |
1: 500-1: 1000 |
brain |
|
IF |
Mouse, Rat |
1: 500-1: 1000 |
brain, hippocampus |
Background
Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Images
|
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Immunohistochemistry analysis of paraffin-embedded mouse brain using Iba1 (GB12105) at dilution of 1: 1000
|
|
Immunohistochemistry analysis of paraffin-embedded rat brain using Iba1 (GB12105) at dilution of 1: 1000 |
|
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Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using Iba1 (GB12105) at dilution of 1: 1000 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed rat brain using Iba1 (GB12105) at dilution of 1: 1000 |
|
Immunofluorescent analysis of paraformaldehyde-fixed rat hippocampus using Neun (GB11138) (green) + Iba1 (GB12105) (red) + MBP (GB12226) (spred) + GFAP (GB11096) (yellow) and Dapi in blue at dilution of 1: 1000 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed rat brain using Neun (GB11138) (green)+ Iba1 (GB12105) (spred) + MAP2 (GB11128-2) (red) and Dapi in blue at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
Publications:
|
|
Title |
Journal |
Pubmed ID |
Application |
|
1 |
Sodium para-aminosalicylic acid inhibits manganese-induced NLRP3 inflammasome-dependent pyroptosis by inhibiting NF-κB pathway activation and oxidative stress. |
Journal of Neuroinflammation |
33203418 |
IF |
|
2 |
Light Emitting Diode Therapy Protects against Myocardial Ischemia/Reperfusion Injury through Mitigating Neuroinflammation. |
Oxidative Medicine and Cellular Longevity |
32963707 |
IF |
|
3 |
Hydrogen Sulfide Reduces Cognitive Impairment in Rats After Subarachnoid Hemorrhage by Ameliorating Neuroinflammation Mediated by the TLR4/NF-κB Pathway in Microglia. |
Frontiers in Cellular Neuroscience |
32754015 |
IF |
|
4 |
Activation of PPAR-β/δ Attenuates Brain Injury by Suppressing Inflammation and Apoptosis in a Collagenase-Induced Intracerebral Hemorrhage Mouse Model. |
Neurochemical Research |
31939088 |
IF |
|
5 |
Clemastine improves hypomyelination in rats with hypoxic-ischemic brain injury by reducing microglia-derived IL-1β via P38 signaling pathway. |
Journal of Neuroinflammation |
32061255 |
IF |
|
6 |
Light-emitting diode therapy protects against ventricular arrhythmias by neuro-immune modulation in myocardial ischemia and reperfusion rat model. |
Journal of Neuroinflammation |
31287006 |
IF |
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