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产品详情
操作说明
注意事项
Product Information
|
Description |
EGFR mouse monoclonal |
|
Protein full name |
Epidermal growth factor receptor |
|
Synonyms |
EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA, epidermal growth factor receptor |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human EGFR |
|
Isotype |
IgG |
|
Subcellular location |
Cytoplasm, Nucleus, Cell membrane, Secreted |
|
Predicted MW. |
134 kDa |
|
Observed MW. |
175 kDa |
|
Purity |
Affinity purification |
|
Uniprot ID |
Applications
| applications | species | dilution | Positive tissue |
| WB | Human | 1: 500-1: 1000 | A549, HepG2, A431 |
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Images
|
Western blot analysis of EGFR (GB12084) at dilution of 1: 1000 Lane 1: A549 cell lysate Lane 2: HepG2 cell lysate Lane 3: A431 cell lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室