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Product Information
Description |
E cadherin mouse monoclonal |
Protein full name |
Cadherin-1 |
Synonyms |
CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO, cadherin 1, BCDS1, E-Cadherin, CAM 120/80, Epithelial cadherin |
Immunogen |
Recombinant protein corresponding to Mouse E-cadherin |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cell junction, Cytoplasm |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Mouse, Rat
|
1: 500-1: 1000 |
colon, brain |
IF |
Mouse, Rat
|
1: 500-1: 1000 |
colon, brain |
Background
Cadherins are calcium-dependent cell adhesion proteins . They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Images
|
Immunohistochemistry analysis of paraffin-embedded human colon using ECAD (GB12082) at dilution of 1: 1000 |
Immunohistochemistry analysis of paraffin-embedded mouse brain using ECAD (GB12082) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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