服务热线
400-1016-218
全国统一服务热线
400-1016-218
科研好帮手 专业生产商
本公司产品仅供科研使用
Product Information
Description |
14-3-3 Tau rabbit polyclonal |
Protein full name |
14-3-3 protein theta |
Synonyms |
14-3-3 protein tau, Ywhaq |
Immunogen |
Recombinant protein corresponding to Mouse 14-3-3 Tau |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
28 kDa |
Observed MW. |
28 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, lung, thymus |
Background
The 14-3-3 family of proteins are important regulatory molecules ubiquitiously expressed in all eukarryotic cells which bind to numerous signaling proteins in various pathways driving critical cellular pathways of apoptosis, differentiation and cell cycle. 14-3-3 theta specifically has also been shown to play an important regulatory role in the TLR2 signaling pathways as a negative regulator of TLR2 ligand Pam3CySk4 induced NF-kB activation. 14-3-3 theta has previously been shown to interact with TLR4 ligand and MyD88 dependent phosphorylated PkC epsilon. 14-3-3 theta in the TLR4 signaling pathway is a positive regulator controlling release of IRF3 indcuded pro-inflammatory cytokines RANTES and IP-10.
Images
Western blot analysis of 14-3-3 Tau (GB111166) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
合肥万物生物科技有限公司
客服热线:400-1016-218
QQ:355185756
地址:安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室